The ability to specify a pressure condition at one or more boundaries of a computational region is an important and useful computational tool. Pressure boundaries represent such things as confined reservoirs of fluid, ambient laboratory conditions, and applied pressures arising from mechanical devices.
Generally, a pressure condition cannot be used at a boundary where velocities are also specified, because velocities are influenced by pressure gradients. The only exception is when pressures are necessary to specify the fluid properties, e.g., density crossing a boundary through an equation of state.