Dissolution

Medical Test Strips

Medical test strips used for rapid diagnostics and determination of relevant biomedical parameters have undergone considerable advances in recent years. Far from the conventional strips with absorbent fleece, new precisely-fabricated microchannels, with defined geometric structures, are now possible via Microsystems engineering. Proper geometrical design of these microstructures enables selective control of the capillary-driven flows. FLOW-3D can be used to optimize the designs of these strips.

Salt dissolution simulation of medical test strips

Regardless of the type of solid, whether it is salt or acetaminophen, penicillin, or sugar, understanding how fast and how much of the solid gets dissolved into the flow is important for several applications areas, especially in medicine. The way in which the solid dissolves could lead to high blood pressure, liver or kidney strain. Also, many pharmaceutical pills are more dense or water-soluble than others and these properties directly affect how the solid interacts with the surrounding medium. All of these parameters are easily varied in FLOW-3D.

FLOW-3D‘s meshing method has solid geometry independence using the FAVOR™ method, and so the area and volume fractions that make up the geometry are simply rewritten at every time step as salt is dissolved from the surface. This makes the simulation very computationally efficient because no mesh refinement is required.

Read more about the Salt Dissolution model in the Modeling Capabilities section.