Modeling Nasal Passages
Nasal drug delivery system, a promising non-invasive means of administrating drugs, poses numerous design challenges. If the spray particles are too large they tend to deposit in the anterior portion of the nasal cavity which reduces the effectiveness of the drug. If the particles are too small, a majority of the particles could pass directly to the lungs wasting most of the dose. For some drugs it is desirable to target a specific region of the nasal cavity like the olfactory region, which has a potential of delivering drugs directly to the brain. Designing a successful nasal drug delivery system requires optimizing various factors such as drug particle size, particle speed, spray angle, and nozzle insertion depth. Using FLOW-3D, the effects of the various design parameters on the system can be easily studied by running a series of simulations.